Evidence for Clonal Dissemination of the Serotype K1 Klebsiella pneumoniae Strain Causing Invasive Liver Abscesses in Korea
نویسندگان
چکیده
منابع مشابه
Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess.
BACKGROUND Primary pyogenic liver abscess (PLA) caused by Klebsiella pneumoniae is an emerging infectious disease. Capsular serotype K1 and the magA gene have been reported to be associated with this disease. METHODS The prevalence of magA was determined by polymerase chain reaction (PCR). The sequences of the magA flanking region were completed by inverse PCR and direct sequencing. Serotypin...
متن کاملSurface antigens contribute differently to the pathophysiological features in serotype K1 and K2 Klebsiella pneumoniae strains isolated from liver abscesses
BACKGROUND The virulence role of surface antigens in a single serotype of Klebsiella pneumoniae strain have been studied, but little is known about whether their contribution will vary with serotype. METHOD To investigate the role of K and O antigen in hyper-virulent strains, we constructed O and K antigen deficient mutants from serotype K1 STL43 and K2 TSGH strains from patients with liver a...
متن کاملRevisiting the importance of virulence determinant magA and its surrounding genes in Klebsiella pneumoniae causing pyogenic liver abscesses: exact role in serotype K1 capsule formation.
BACKGROUND Mucoviscosity-associated gene A (magA) is proposed to play a decisive role in the pathogenesis of liver abscesses due to Klebsiella pneumoniae. Although some investigators consider MagA to be a putative O-antigen ligase, it is also reportedly associated with the K1 antigen. METHODS Using magA-positive serotype K1 K. pneumoniae STL43 isolated from a patient with liver abscess, we co...
متن کاملKlebsiella pneumoniae–Induced Liver Abscesses, Germany
To The Editor: Monomicrobial liver abscesses caused by Klebsiella pneumoniae are an emerging problem in Asia. Among 77 capsular types of Klebsiella spp., K1 and K2 are the most virulent (1–3). In Asia, isolated strains are mainly serotype K1, followed by K2. In Taiwan, about 63.4% of liver abscesses caused by K. pneu-moniae are associated with K1 strains and 14.2% by K2 (4); no comparable epide...
متن کاملLiver abscess associated with severe myopathy caused by Klebsiella pneumoniae serotype K1 in Romania.
Liver abscess was diagnosed in a man presenting with fever, chills and severe myopathy. The K. pneumoniae isolated from blood cultures belonged to the K1 serotype. The patient responded favourably to percutaneous drainage of the abscess and antibiotics. This is the first documented report of Klebsiella pneumoniae liver abscess syndrome (KLAS) described in Romania and may indicate the emergence ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2008
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.01577-08